PMID:358200
| Citation |
Sutcliffe, JG (1978) Nucleotide sequence of the ampicillin resistance gene of Escherichia coli plasmid pBR322. Proc. Natl. Acad. Sci. U.S.A. 75:3737-41 |
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| Abstract |
I have determined the nucleotide sequence of the ampicillin resistance gene of pBR322, an Escherichia coli plasmid that encodes a penicillin beta-lactamase. This gene codes for a protein of 286 amino acid residues. The first 23 amino acids presumably form a signal for secretion, because they do not appear in the mature enzyme, whose partial amino acid sequence has been determined independently. |
| Links | |
| Keywords |
Ampicillin; Base Sequence; Escherichia coli/genetics; Genes; Penicillin Resistance; Plasmids; beta-Lactamases/genetics |
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