PMID:342516
| Citation |
Long, WS, Slayman, CL and Low, KB (1978) Production of giant cells of Escherichia coli. J. Bacteriol. 133:995-1007 |
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| Abstract |
Giant cells, with volumes up to 500-fold those of normal cells, have been produced by both genetic and pharmacological means in Escherichia coli K-12. In the genetic approach, an envB or mon mutation (conferring rounded or irregular morphology) was combined with a lon mutation (block of septation after irradiation). UV irradiation and subsequent incubation for 2 to 5 h in a rich medium supplemented with 1% sodium chloride led t; production of polymorphic giant cells. In the pharmacological approach, incubation of several different strains of E. coli K-12 with the drug 6-amidinopenicillanic acid (FL1060) in the same rich medium gave rise to a homogeneous population of smoothly rounded giant cells. |
| Links | |
| Keywords |
Cell Division; Escherichia coli/cytology; Escherichia coli/genetics; Escherichia coli/radiation effects; Microscopy, Phase-Contrast; Mutation; Phenotype; Transduction, Genetic; Ultraviolet Rays |
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