PMID:339828
| Citation |
Hoekstra, WP and Vis, HG (1977) Characterization of the E. coli K12 strain AB1157 as impaired in guanine/xanthine metabolism. Antonie Van Leeuwenhoek 43:199-204 |
|---|---|
| Abstract |
The widely used E. coli K12 strain AB1157 is impaired in guanine (xnathine) metabolism. Mutants blocked in purine biosynthesis before the stage of inosine monophosphate synthesis do not grow on external guanine or xanthine. The genetic nature of the Gua/Xan lesion is a deletion in the chromosome that covers the proA gene. The lesion causes reduced uptake of guanine. |
| Links | |
| Keywords |
Chromosome Mapping; Chromosomes, Bacterial; Escherichia coli/genetics; Escherichia coli/metabolism; Genes; Guanine/metabolism; Mutation; Pentosyltransferases/metabolism; Xanthines/metabolism |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
References
See Help:References for how to manage references in EcoliWiki.