PMID:3283106
| Citation |
Dai, D and Ishiguro, EE (1988) murH, a new genetic locus in Escherichia coli involved in cell wall peptidoglycan biosynthesis. J. Bacteriol. 170:2197-201 |
|---|---|
| Abstract |
A temperature-sensitive mutant of Escherichia coli defective in peptidoglycan synthesis was characterized. The incorporation of radiolabeled meso-diaminopimelate into peptidoglycan by the mutant was inhibited at the restrictive growth temperature, resulting in autolysis. The defective step appeared to be part of the terminal stage in peptidoglycan synthesis involving the incorporation of disaccharide peptide units into the wall peptidoglycan. The mutation was assigned to a new locus, designated murH, at 99.2 min on the E. coli linkage map. |
| Links | |
| Keywords |
Cell Wall; Chromosome Mapping; Escherichia coli/genetics; Escherichia coli/metabolism; Escherichia coli/ultrastructure; Genes, Bacterial; Mutation; Peptidoglycan/biosynthesis; Phenotype; Temperature |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
References
See Help:References for how to manage references in EcoliWiki.