PMID:3275618

Citation	Palchaudhuri, S, Patel, V and McFall, E (1988) DNA sequence of the D-serine deaminase activator gene dsdC. J. Bacteriol. 170:330-4
Abstract	We have determined the DNA sequence of dsdC, the gene that encodes the D-serine deaminase activator protein of Escherichia coli K-12. The sequence contains a single open reading frame that terminates in a UGA codon. One the basis of the size of the protein, 33 kilodaltons, and the amino acid sequence encoded by the open reading frame, we identified a likely translation initiation codon 731 base pairs upstream of the translation initiation codon for the divergently transcribed D-serine deaminase gene. There is a broad range of codon usage, not surprising in view of the weak expression of the gene. The N-terminal two-thirds of the activator is arginine-lysine rich and quite polar; the remainder is more neutral. The segment of the protein that seems most likely to have potential to form the helix-turn-helix structure characteristic of DNA-regulatory proteins is located near the end of the polar region. The protein contains a region with significant homology to lambda attB.
Links	PubMed PMC210646
Keywords	Amino Acid Sequence; Base Sequence; Codon/genetics; DNA, Bacterial/genetics; DNA-Binding Proteins/genetics; Escherichia coli/enzymology; Escherichia coli/genetics; Genes, Bacterial; Molecular Sequence Data; Protein Biosynthesis; Sequence Homology, Nucleic Acid; Transcription Factors/genetics
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