PMID:3127383

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Citation

Peterson, KR, Ossanna, N and Mount, DW (1988) The Escherichia coli K-12 lexA2 gene encodes a hypocleavable repressor. J. Bacteriol. 170:1975-7

Abstract

LexA2 repressor was partially inactivated after mitomycin C or UV light treatment in a recA+ or recA85(Prtc) (protease constitutive) host background. LexA2 protein was cleaved, but the reaction was slower than that observed for LexA+ repressor. lexA2 had a C-to-T transition at nucleotide 461 (Thr-154 to Ile).

Links

PubMed PMC211063

Keywords

Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Escherichia coli/drug effects; Escherichia coli/genetics; Escherichia coli/radiation effects; Gene Expression Regulation; Genes, Bacterial; Mitomycin; Mitomycins/pharmacology; Mutation; Repressor Proteins/genetics; Repressor Proteins/metabolism; SOS Response (Genetics); Serine Endopeptidases; Transcription Factors/genetics; Ultraviolet Rays

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