PMID:3126825

Citation	Springer, M, Graffe, M, Mayaux, JF, Dardel, F, Fayat, G, Blanquet, S and Grunberg-Manago, M (1987) Open reading frames in the control regions of the phenylalanyl-tRNA synthetase operon of E. coli. Biochimie 69:1065-70
Abstract	The pheST operon codes for the two subunits of phenylalanyl-tRNA synthetase and it expression is controlled by attenuation in a way similar to many amino acid biosynthetic operons. The nucleotide sequence of the control regions of the operon indicates the presence of several open reading frames besides that of the leader peptide. One of these open reading frames, called the alternative leader peptide, starts at about the same place as the leader peptide and ends after the terminator of the attenuator. Another open reading frame, called the terminator peptide, starts after the terminator and covers about half the distance to pheS, the first structural gene of the operon. The present report shows that, in fact, the only open reading frame to be translated efficiently is the leader peptide itself. The alternative leader peptide and the terminator peptide are both translated at a negligible rate.
Links	PubMed
Keywords	Amino Acyl-tRNA Synthetases/genetics; Base Sequence; Escherichia coli/genetics; Molecular Sequence Data; Operon; Phenylalanine-tRNA Ligase/genetics; beta-Galactosidase/analysis; beta-Lactamases/analysis
edit table

Significance

You can help EcoliWiki by summarizing why this paper is useful

You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.

Add links to pages that link here (e.g. gene, product, method pages)

See Help:References for how to manage references in EcoliWiki.