PMID:3102747
| Citation |
Rousset, JP, Gilson, E and Hofnung, M (1986) malM, a new gene of the maltose regulon in Escherichia coli K12. II. Mutations affecting the signal peptide of the MalM protein. J. Mol. Biol. 191:313-20 |
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| Abstract |
malM is the last gene of the malK-lamB-malM operon of Escherichia coli K12. It encodes a periplasmic protein. Mutations affecting the hydrophobic core of the N-terminal extension of the MalM protein have been isolated. They result in an increase in amount and specific activity of a MalM-LacZ hybrid protein. This result confirms that the signal peptide of the MalM protein is functional. |
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| Keywords |
Base Sequence; DNA, Bacterial; Escherichia coli/enzymology; Escherichia coli/genetics; Genes, Bacterial; Maltose/genetics; Mutation; Phenotype; Protein Biosynthesis; Protein Sorting Signals/genetics; Terminator Regions, Genetic; beta-Galactosidase/metabolism |
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