PMID:3086742

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Citation

Normanly, J, Ogden, RC, Horvath, SJ and Abelson, J Changing the identity of a transfer RNA. Nature 321:213-9

Abstract

A leucine transfer RNA has been transformed into a serine transfer RNA by changing 12 nucleotides. This result indicates that a limited set of residues determine tRNA identity.

Links

PubMed Online version:10.1038/321213a0

Keywords

Amino Acyl-tRNA Synthetases/metabolism; Anticodon; Base Sequence; Codon; Escherichia coli/genetics; Leucine; Nucleic Acid Conformation; Protein Biosynthesis; RNA, Transfer/genetics; RNA, Transfer/metabolism; Serine; Structure-Activity Relationship; Substrate Specificity; Suppression, Genetic

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