PMID:3079182

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Citation

Sukhodolets, VV (1988) Organization and evolution of the bacterial genome. Microbiol. Sci. 5:202-6

Abstract

The bacterial chromosome seems to be organized in such a way as to allow the formation of tandem gene duplications, which appear under conditions of positive selection for a high level of gene expression. Multiple gene duplications permit the excision of a gene from the chromosome by a Campbell recombinational event and the subsequent transfer of the gene to a resident plasmid. The latter derives an advantage from carrying a gene providing positive selection. Thus, tandem gene duplications could initiate horizontal gene transfer in bacteria.

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Keywords

Bacteria/genetics; Biological Evolution; Chromosomes/ultrastructure; Genes, Bacterial

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