PMID:3076377

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Citation

Siggaard-Andersen, M (1988) Role of Escherichia coli beta-ketoacyl-ACP synthase I in unsaturated fatty acid synthesis. Carlsberg Res. Commun. 53:371-9

Abstract

Two activities were found in E. coli extracts which could complement unsaturated fatty acid synthesis of a cerulenin treated E. coli fatty acid synthetase. One of these is beta-ketoacyl-ACP synthase I, but it is not known whether the other activity represents the previously characterized beta-ketoacyl-ACP synthase II. A mutant strain exhibiting a temperature sensitive unsaturated fatty acid synthetic activity apparently lacked an active beta-ketoacyl-ACP synthase I.

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Keywords

3-Oxoacyl-(Acyl-Carrier-Protein) Synthase/metabolism; 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase/physiology; Acyltransferases/physiology; Cerulenin/metabolism; Escherichia coli/enzymology; Escherichia coli/genetics; Fatty Acids, Unsaturated/biosynthesis; Mutation

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