PMID:3062310
| Citation |
Overduin, P, Boos, W and Tommassen, J (1988) Nucleotide sequence of the ugp genes of Escherichia coli K-12: homology to the maltose system. Mol. Microbiol. 2:767-75 |
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| Abstract |
The nucleotide sequence of the ugp genes of Escherichia coli K-12, which encode a phosphate-limitation inducible uptake system for sn-glycerol-3-phosphate and glycerophosphoryl diesters, was determined. The genetic organization of the operon differed from previously published results. A single promoter, containing a putative pho box, was detected by S1-nuclease mapping. The promoter is followed by four open reading frames, designated ugpB, A, E and C, which encode a periplasmic binding protein, two hydrophobic membrane proteins and a protein that is likely to couple energy to the transport system, respectively. The sequences of the proteins contain the characteristics of several other binding protein-dependent transport systems, but they seem to be particularly closely related to the maltose system. |
| Links | |
| Keywords |
Amino Acid Sequence; Base Sequence; Biological Transport, Active; DNA, Bacterial/genetics; Escherichia coli/genetics; Escherichia coli/metabolism; Genes, Bacterial; Glycerophosphates/pharmacokinetics; Maltose/pharmacokinetics; Molecular Sequence Data; Phosphates/metabolism; Promoter Regions, Genetic; Restriction Mapping; Sequence Homology, Nucleic Acid |
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