PMID:3049557
| Citation |
Lieb, M and Bhagwat, AS (1988) Very short patch mismatch repair activity associated with gene dcm is not conferred by a plasmid coding for EcoRII methylase. J. Bacteriol. 170:4967-8 |
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| Abstract |
The only cytosine methylase in Escherichia coli K-12 methylates the second cytosine in the sequence CC (A/T)GG and is encoded by gene dcm. Methylation and very short patch mismatch repair activities lacking in a dcm mutant of E. coli were restored by a plasmid containing the cloned dcm gene. In contrast, plasmids with the gene for EcoRII methylase, which is a homolog of dcm, restored only cytosine methylase activity and not mismatch repair. |
| Links | |
| Keywords |
DNA (Cytosine-5-)-Methyltransferase/metabolism; DNA Repair; DNA-Cytosine Methylases/genetics; Deoxyribonucleases, Type II Site-Specific; Escherichia coli/genetics |
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