PMID:2696058
| Citation |
Baril, C, Richaud, C, Baranton, G and Saint Girons, IS (1989) Linear chromosome of Borrelia burgdorferi. Res. Microbiol. 140:507-16 |
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| Abstract |
The DNA organization of several European and American isolates of Borrelia burgdorferi, the aetiological agent of Lyme disease, was analysed in pulse-field agarose gel electrophoresis. The results of in situ cell lysis in agarose plugs demonstrated a unique arrangement for the DNA of this spirochete. The chromosome of Borrelia behaved as a eukaryotic linear chromosome with a size of around 1,000 kb. The genome also comprised several circular and linear plasmids which varied in size from 15 to 60 kb. |
| Links | |
| Keywords |
Borrelia burgdorferi Group/genetics; DNA, Bacterial/isolation & purification; Electrophoresis, Agar Gel; Molecular Weight; Nucleic Acid Hybridization; Plasmids/genetics; Restriction Mapping |
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