PMID:2692566
| Citation |
Grant, GA (1989) A new family of 2-hydroxyacid dehydrogenases. Biochem. Biophys. Res. Commun. 165:1371-4 |
|---|---|
| Abstract |
The NADH-dependent hydroxypyruvate reductase from cucumber and the pdxB gene product of E. coli display significant homology to E. coli D-3-phosphoglycerate dehydrogenase. In contrast, these proteins do not display much similarity with other oxidoreductases or with other 2-hydroxyacid dehydrogenases in particular. On the basis of their relatedness and the structure of their substrates, these three enzymes constitute a new family of 2-hydroxyacid dehydrogenases distinct from malate and lactate dehydrogenase. |
| Links | |
| Keywords |
Adenosine Monophosphate/metabolism; Alcohol Oxidoreductases; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Carbohydrate Dehydrogenases/genetics; Escherichia coli/enzymology; Escherichia coli Proteins; Hydroxypyruvate Reductase; L-Lactate Dehydrogenase; Malate Dehydrogenase; Molecular Sequence Data; NAD/pharmacology; Phosphoglycerate Dehydrogenase; Plants/enzymology; Pyridoxine/biosynthesis; Sequence Homology, Nucleic Acid |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
References
See Help:References for how to manage references in EcoliWiki.