PMID:2659328
| Citation |
Witkin, EM (1989) Ultraviolet mutagenesis and the SOS response in Escherichia coli: a personal perspective. Environ. Mol. Mutagen. 14 Suppl 16:30-4 |
|---|---|
| Abstract |
The study of ultraviolet (UV) mutagenesis in Escherichia coli began with the assumption that genes were likely to be changed at the instant of photon absorption. Over many decades, it became clear that postirradiation cellular activities, including enzymatic DNA repair of UV photo products and error-prone modes of tolerating unrepaired DNA lesions can exert profound influences on the mutagenic outcome of irradiation. Current study focusses on the molecular details of radiation-induced translesion DNA replication as the final event in UV mutagenesis. |
| Links | |
| Keywords |
DNA Repair; Escherichia coli/radiation effects; History, 20th Century; Mutagenicity Tests/history; Mutagens; Mutation; SOS Response (Genetics); Ultraviolet Rays; United States |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
See also
References
See Help:References for how to manage references in EcoliWiki.