PMID:2530497

Citation	Naom, IS, Morton, SJ, Leach, DR and Lloyd, RG (1989) Molecular organization of sbcC, a gene that affects genetic recombination and the viability of DNA palindromes in Escherichia coli K-12. Nucleic Acids Res. 17:8033-45
Abstract	The sbcC gene product of Escherichia coli interferes with the growth of a lambda red gam phage carrying a long palindrome in its DNA. This phenotype was used to identify recombinant plasmids harbouring the wild-type gene and to isolate sbcC mutant derivatives carrying Tn1000 insertions. Analysis of these plasmids located sbcC between proC and phoR at a slightly different position from that reported before (Lloyd, R.G. and Buckman, C. 1985, J. Bacteriol. 164, 836-844). Nucleotide sequencing revealed that the gene spans a DNA segment of 3.3 kb that encodes a poorly expressed protein of 118 kDa and which lies downstream of a gene of unknown function that encodes a polypeptide of 45 kDa. The amino acid sequence of SbcC contains a nucleotide binding fold similar to that in RecB and other recombination proteins.
Links	PubMed PMC334945
Keywords	Amino Acid Sequence; Bacterial Proteins/genetics; Bacteriophage lambda/genetics; Base Sequence; Cloning, Molecular; DNA/genetics; DNA, Viral/genetics; Deoxyribonucleases; Escherichia coli/genetics; Escherichia coli Proteins; Genes, Bacterial; Genetic Markers/analysis; Genotype; Molecular Sequence Data; Plasmids; Recombination, Genetic; Restriction Mapping
edit table

Significance

You can help EcoliWiki by summarizing why this paper is useful

You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.

Add links to pages that link here (e.g. gene, product, method pages)

See Help:References for how to manage references in EcoliWiki.