PMID:2515414
| Citation |
Dewar, SJ, Kagan-Zur, V, Begg, KJ and Donachie, WD (1989) Transcriptional regulation of cell division genes in Escherichia coli. Mol. Microbiol. 3:1371-7 |
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| Abstract |
The complete Escherichia coli ftsQ coding sequence, together with part of the ftsA coding sequence, has been cloned upstream of the lacZ open reading frame in a lambda-vector (lambda JFL100). Cells which are lysogenic for lambda JFL100 transcribe the cloned lacZ from promoter(s) within the ftsQ and ftsA sequences. The level of beta-galactosidase produced is dependent on growth rate (and/or cell size) and is derepressed in an ftsA-deficient mutant. Transcription during the cell cycle is restricted to the time of cell division. |
| Links | |
| Keywords |
Cell Division; DNA Replication; Escherichia coli/genetics; Gene Expression Regulation, Bacterial; Genes, Regulator; Repressor Proteins/physiology; Restriction Mapping; Transcription, Genetic; beta-Galactosidase/biosynthesis |
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