PMID:2280345
| Citation |
Jung, H, Jung, K and Kleber, HP (1990) L-carnitine metabolization and osmotic stress response in Escherichia coli. J. Basic Microbiol. 30:409-13 |
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| Abstract |
Growth of Escherichia coli 044 K 74 in liquid medium of raised osmotic strength was stimulated by exogenous L-carnitine, crotonobetaine and gamma-butyrobetaine, respectively. L-Carnitine was accumulated within the cells in dependence on the salt concentration of the media. Osmotic stress during aerobic or anaerobic growth with glucose triggered the L-carnitine uptake in E. coli 044 K 74 whereas L-carnitine uptake by cells of this organism grown anaerobically on glycerol/fumarate was only slightly modified. Synthesis of the enzymes metabolizing L-carnitine to gamma-butyrobetaine in glycerol/fumarate growing bacteria was found to be completely repressed by high NaCl-concentrations. Together, these results indicate that most likely the L-carnitine metabolization sequence does not play a role in osmoregulation in E. coli 044 K 74. |
| Links | |
| Keywords |
Acyltransferases; Carnitine/metabolism; Culture Media; Enzyme Induction/drug effects; Escherichia coli/metabolism; Escherichia coli/physiology; Hydro-Lyases/biosynthesis; Multienzyme Complexes; Osmolar Concentration; Oxidoreductases/metabolism; Sodium Chloride/pharmacology; Water-Electrolyte Balance |
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