PMID:22308720

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Citation

'Andriushchenko, SV, Bukharin, OV, Perunova, NB and Ivanova, EV [The increase of plasmid DNA copy number is a possible mechanism of the amplification of bacteria anti-lysozyme activity under the effect of chloramphenicol]. Zh. Mikrobiol. Epidemiol. Immunobiol. ':8-13

Abstract

Determination of copy number dynamics of plasmid DNA and anti-lysozyme activityunderthe influence of chloramphenicol in cells of Escherichia coli 252 and 242 strains (ICIS), that have identical biochemical profile and differ by antibiotic resistance, plasmid profile and level of anti-lysozyme activity.

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Keywords

Chloramphenicol/pharmacology; Culture Media; DNA, Bacterial/genetics; Drug Resistance, Bacterial; Electrophoresis, Agar Gel; Escherichia coli/drug effects; Escherichia coli/genetics; Escherichia coli/isolation & purification; Gene Dosage; Humans; Microbial Sensitivity Tests; Muramidase/genetics; Plasmids/genetics

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