PMID:22143262

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Citation

Yamamura, H, Suzuki, K, Uchibori, K, Miyagawa, A, Kawai, M, Ohmizo, C and Katsu, T (2012) Mimicking an antimicrobial peptide polymyxin B by use of cyclodextrin. Chem. Commun. (Camb.) 48:892-4

Abstract

Cyclodextrin derivatives prepared to mimic a membrane active antibacterial peptide polymyxin B strongly permeabilized bacterial membrane and inhibited bacterial proliferation.

Links

PubMed Online version:10.1039/c1cc16369h

Keywords

Anti-Bacterial Agents/chemistry; Anti-Bacterial Agents/pharmacology; Cell Membrane Permeability/drug effects; Cyclodextrins/chemistry; Cyclodextrins/pharmacology; Escherichia coli/drug effects; Escherichia coli/metabolism; Microbial Sensitivity Tests; Polymyxin B/analogs & derivatives; Polymyxin B/chemistry; Polymyxin B/pharmacology; Potassium/metabolism; Staphylococcus aureus/drug effects; Staphylococcus aureus/metabolism

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