PMID:22044664

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Citation

Baumler, DJ, Peplinski, RG, Reed, JL, Glasner, JD and Perna, NT (2011) The evolution of metabolic networks of E. coli. BMC Syst Biol 5:182

Abstract

Despite the availability of numerous complete genome sequences from E. coli strains, published genome-scale metabolic models exist only for two commensal E. coli strains. These models have proven useful for many applications, such as engineering strains for desired product formation, and we sought to explore how constructing and evaluating additional metabolic models for E. coli strains could enhance these efforts.

Links

PubMed PMC3229490 Online version:10.1186/1752-0509-5-182

Keywords

Escherichia coli/genetics; Escherichia coli/metabolism; Evolution, Molecular; Genome, Bacterial; Metabolic Networks and Pathways; Models, Biological; Phylogeny; Salmonella/genetics; Salmonella/metabolism

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