PMID:2200166
| Citation |
Farber, GK and Petsko, GA (1990) The evolution of alpha/beta barrel enzymes. Trends Biochem. Sci. 15:228-34 |
|---|---|
| Abstract |
Of the enzymes whose structure is known, roughly one out of ten has an eight-stranded alpha/beta barrel domain. Structural and chemical evidence suggests that all of these domains may have diverged from a common ancestor. |
| Links | |
| Keywords |
Amino Acid Sequence; Biological Evolution; Enzymes/genetics; Isomerases/genetics; Lyases/genetics; Molecular Sequence Data; Oxidoreductases/genetics; Protein Conformation; Structure-Activity Relationship; Triose-Phosphate Isomerase/genetics |
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