PMID:21939518

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Citation

Shalá, AA, Restrepo, S and González Barrios, AF (2011) A network model for biofilm development in Escherichia coli K-12. Theor Biol Med Model 8:34

Abstract

In nature, bacteria often exist as biofilms. Biofilms are communities of microorganisms attached to a surface. It is clear that biofilm-grown cells harbor properties remarkably distinct from planktonic cells. Biofilms frequently complicate treatments of infections by protecting bacteria from the immune system, decreasing antibiotic efficacy and dispersing planktonic cells to distant body sites. In this work, we employed enhanced Boolean algebra to model biofilm formation.

Links

PubMed PMC3224578 Online version:10.1186/1742-4682-8-34

Keywords

Biofilms/growth & development; Escherichia coli K12/genetics; Escherichia coli K12/physiology; Gene Knockout Techniques; Gene Regulatory Networks/genetics; Models, Biological; Multigene Family

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