PMID:21899540
| Citation |
Ryan, EM, Gorman, SP, Donnelly, RF and Gilmore, BF (2011) Recent advances in bacteriophage therapy: how delivery routes, formulation, concentration and timing influence the success of phage therapy. J. Pharm. Pharmacol. 63:1253-64 |
|---|---|
| Abstract |
Bacteriophages are bacteria-specific viruses that infect and, in the case of obligately lytic phages, destroy their host bacteria. Phage therapy has been used therapeutically to combat bacterial infections since their discovery. This paper reviewed recent in-vivo phage therapy studies, with a distinct focus on the effect of delivery routes, phage concentration and timing of administration on the success of the therapy. |
| Links |
PubMed Online version:10.1111/j.2042-7158.2011.01324.x |
| Keywords |
Animals; Bacterial Infections/therapy; Bacteriophages; Biofilms/growth & development; Biological Therapy/methods; Drug Administration Routes; Drug Administration Schedule; Equipment and Supplies/microbiology; Humans |
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