PMID:21835771
| Citation |
Mäkelä, J, Huttunen, H, Kandhavelu, M, Yli-Harja, O and Ribeiro, AS (2011) Automatic detection of changes in the dynamics of delayed stochastic gene networks and in vivo production of RNA molecules in Escherichia coli. Bioinformatics 27:2714-20 |
|---|---|
| Abstract |
Production and degradation of RNA and proteins are stochastic processes, difficulting the distinction between spurious fluctuations in their numbers and changes in the dynamics of a genetic circuit. An accurate method of change detection is key to analyze plasticity and robustness of stochastic genetic circuits. |
| Links |
PubMed Online version:10.1093/bioinformatics/btr471 |
| Keywords |
Algorithms; Escherichia coli/genetics; Gene Expression Regulation; Gene Regulatory Networks/genetics; Gene Silencing; Humans; Models, Genetic; Proteins/genetics; RNA/biosynthesis; RNA/genetics; Saccharomyces cerevisiae/genetics; Stochastic Processes |
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