PMID:2181232

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Citation

Sharp, PM (1990) Processes of genome evolution reflected by base frequency differences among Serratia marcescens genes. Mol. Microbiol. 4:119-22

Abstract

The G + C content of silent sites in codons varies greatly among Serratia marcescens genes; the value in any one gene seems to reflect a balance between mutation pressure towards high G + C content and natural selection constraining choice among synonymous codons. Interestingly, non-coding sequences have substantially lower G + C content than silent sites thought to be under little selective constraint.

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Keywords

Base Composition; Biological Evolution; Codon; Genes, Bacterial; Serratia marcescens/genetics

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