PMID:21799784

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Citation

Deghorain, M, Pagès, C, Meile, JC, Stouf, M, Capiaux, H, Mercier, R, Lesterlin, C, Hallet, B and Cornet, F (2011) A defined terminal region of the E. coli chromosome shows late segregation and high FtsK activity. PLoS ONE 6:e22164

Abstract

The FtsK DNA-translocase controls the last steps of chromosome segregation in E. coli. It translocates sister chromosomes using the KOPS DNA motifs to orient its activity, and controls the resolution of dimeric forms of sister chromosomes by XerCD-mediated recombination at the dif site and their decatenation by TopoIV.

Links

PubMed PMC3140498 Online version:10.1371/journal.pone.0022164

Keywords

Chromosome Segregation; Chromosomes, Bacterial/genetics; DNA, Bacterial/genetics; DNA, Bacterial/metabolism; Escherichia coli K12/cytology; Escherichia coli K12/genetics; Escherichia coli K12/metabolism; Escherichia coli Proteins/chemistry; Escherichia coli Proteins/genetics; Escherichia coli Proteins/metabolism; Membrane Proteins/chemistry; Membrane Proteins/genetics; Membrane Proteins/metabolism; Nucleotide Motifs; Protein Structure, Tertiary; Sequence Deletion

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