PMID:21719992
| Citation |
Matsumura, K, Furukawa, S, Ogihara, H and Morinaga, Y (2011) Roles of multidrug efflux pumps on the biofilm formation of Escherichia coli K-12. Biocontrol Sci 16:69-72 |
|---|---|
| Abstract |
We genetically analyzed the roles of multidrug efflux pumps on the biofilm formation of Escherichia coli K-12 BW25113. We used 22 mutants missing various genes related to the multidrug efflux pumps and found that the biofilm formation of emrD, emrE, emrK, acrD, acre and mdtE-deleted mutants was extremely decreased. These results indicate that some multidrug efflux pumps significantly contribute to the biofilm formation of E. coli. |
| Links | |
| Keywords |
Biofilms/growth & development; Drug Resistance, Multiple, Bacterial; Escherichia coli K12/genetics; Escherichia coli K12/growth & development; Gene Deletion; Genes, Bacterial/genetics; Genes, Bacterial/physiology; Genes, MDR/physiology; Hydrophobic and Hydrophilic Interactions; Polystyrenes/chemistry; Surface Properties |
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