PMID:21718539
| Citation |
Angiuoli, SV, Dunning Hotopp, JC, Salzberg, SL and Tettelin, H (2011) Improving pan-genome annotation using whole genome multiple alignment. BMC Bioinformatics 12:272 |
|---|---|
| Abstract |
Rapid annotation and comparisons of genomes from multiple isolates (pan-genomes) is becoming commonplace due to advances in sequencing technology. Genome annotations can contain inconsistencies and errors that hinder comparative analysis even within a single species. Tools are needed to compare and improve annotation quality across sets of closely related genomes. |
| Links |
PubMed PMC3142524 Online version:10.1186/1471-2105-12-272 |
| Keywords |
Bacteria/genetics; Chromosome Mapping; Genome, Bacterial; Molecular Sequence Annotation; Sequence Alignment/methods |
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