PMID:2152914

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Citation

Harkness, RE and Braun, V (1990) In vitro peptidoglycan synthesis by envelopes from Escherichia coli tolM mutants is inhibited by colicin M. J. Bacteriol. 172:498-500

Abstract

An in vitro peptidoglycan synthesis reaction was employed to further characterize the role of the tolM product in colicin M-induced inhibition of peptidoglycan synthesis. It was found that the tolM product is not the colicin M target and that this gene product does not play a role in the interaction of the colicin with its target. Colicin M remained associated with envelopes prepared from colicin-treated tolM mutants. These findings suggested that the tolM product most likely is involved with the internalization of colicin M.

Links

PubMed PMC208462

Keywords

Bacterial Proteins/analysis; Calcium/pharmacology; Colicins/metabolism; Colicins/pharmacology; Escherichia coli/drug effects; Escherichia coli/genetics; Escherichia coli/metabolism; Genes, Bacterial; Mutation; Peptidoglycan/biosynthesis

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