PMID:21460078
| Citation |
Raghavan, R, Sage, A and Ochman, H (2011) Genome-wide identification of transcription start sites yields a novel thermosensing RNA and new cyclic AMP receptor protein-regulated genes in Escherichia coli. J. Bacteriol. 193:2871-4 |
|---|---|
| Abstract |
Intergenic regions often contain regulatory elements that control the expression of flanking genes. Using a deep-sequencing approach, we identified numerous new transcription start sites in Escherichia coli, yielding a new thermosensing regulatory RNA and seven genes previously unknown to be under the control of the global regulator CRP. |
| Links |
PubMed PMC3133129 Online version:10.1128/JB.00398-11 |
| Keywords |
Base Sequence; DNA, Bacterial/chemistry; DNA, Bacterial/genetics; DNA, Intergenic; DNA-Binding Proteins/metabolism; Escherichia coli/genetics; Escherichia coli/radiation effects; Escherichia coli Proteins/metabolism; Gene Expression Regulation, Bacterial; Genes, Bacterial; High-Throughput Nucleotide Sequencing; Nucleic Acid Conformation; RNA/metabolism; Receptors, Cyclic AMP/metabolism; Regulon; Sequence Alignment; Temperature; Transcription Initiation Site |
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