PMID:21439067
| Citation |
Ferenci, T, Galbiati, HF, Betteridge, T, Phan, K and Spira, B (2011) The constancy of global regulation across a species: the concentrations of ppGpp and RpoS are strain-specific in Escherichia coli. BMC Microbiol. 11:62 |
|---|---|
| Abstract |
Sigma factors and the alarmone ppGpp control the allocation of RNA polymerase to promoters under stressful conditions. Both ppGpp and the sigma factor σS (RpoS) are potentially subject to variability across the species Escherichia coli. To find out the extent of strain variation we measured the level of RpoS and ppGpp using 31 E. coli strains from the ECOR collection and one reference K-12 strain. |
| Links |
PubMed PMC3074542 Online version:10.1186/1471-2180-11-62 |
| Keywords |
Bacterial Proteins/analysis; Escherichia coli/chemistry; Escherichia coli/metabolism; Escherichia coli/physiology; Gene Expression Regulation, Bacterial; Genetic Variation; Guanosine Tetraphosphate/analysis; Sigma Factor/analysis |
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