PMID:21169441

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Citation

Hidalgo, G, Ponton, A, Fatisson, J, O'May, C, Asadishad, B, Schinner, T and Tufenkji, N (2011) Induction of a state of iron limitation in uropathogenic Escherichia coli CFT073 by cranberry-derived proanthocyanidins as revealed by microarray analysis. Appl. Environ. Microbiol. 77:1532-5

Abstract

Transcriptional profiles of uropathogenic Escherichia coli CFT073 exposed to cranberry-derived proanthocyanidins (PACs) were determined. Our results indicate that bacteria grown on media supplemented with PACs were iron deprived. To our knowledge, this is the first time that PACs have been shown to induce a state of iron limitation in this bacterium.

Links

PubMed PMC3067223 Online version:10.1128/AEM.02201-10

Keywords

Bacterial Adhesion/drug effects; Gene Expression Profiling; Iron/metabolism; Iron Chelating Agents/pharmacology; Microarray Analysis; Plant Extracts; Proanthocyanidins/pharmacology; Reverse Transcriptase Polymerase Chain Reaction; Uropathogenic Escherichia coli/genetics; Uropathogenic Escherichia coli/growth & development; Uropathogenic Escherichia coli/metabolism; Vaccinium macrocarpon/chemistry

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