PMID:2040436

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Citation

Pascal, MC, Lepelletier, M, Giordano, G and Chippaux, M (1991) A regulatory mutant of the trimethylamine N-oxide reductase of Escherichia coli K12. FEMS Microbiol. Lett. 62:297-300

Abstract

A mutant of Escherichia coli was isolated in which the trimethylamine N-oxide (TMAO) reductase activity is lost and the inducible TMAO reductase protein is absent. The lack of the gene product specifically prevents the expression of torA::lacZ fusion indicating a transcriptional control of torA, the TMAO reductase structural gene. The gene designated torR was mapped at 22 min on the chromosome.

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Keywords

Chromosome Mapping; Escherichia coli/enzymology; Escherichia coli/genetics; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genes, Regulator; Mutation; NADH, NADPH Oxidoreductases/genetics; NADH, NADPH Oxidoreductases/metabolism; Oxidoreductases Acting on CH-NH Group Donors; Transcription, Genetic

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