PMID:20395215
| Citation |
Tavío, MM, Aquili, VD, Poveda, JB, Antunes, NT, Sánchez-Céspedes, J and Vila, J (2010) Quorum-sensing regulator sdiA and marA overexpression is involved in in vitro-selected multidrug resistance of Escherichia coli. J. Antimicrob. Chemother. 65:1178-86 |
|---|---|
| Abstract |
The role of sdiA in the acquisition of low-level multidrug resistance (MDR) was analysed and compared with that of marA and soxS in two Escherichia coli clinical isolates and two in vitro-selected mutants. |
| Links |
PubMed Online version:10.1093/jac/dkq112 |
| Keywords |
2,4-Dinitrophenol/pharmacology; Anti-Bacterial Agents/pharmacology; Ceftazidime/pharmacology; DNA-Binding Proteins/biosynthesis; Drug Resistance, Multiple, Bacterial; Escherichia coli/drug effects; Escherichia coli Proteins/biosynthesis; Fluoroquinolones/pharmacology; Gene Expression; Gene Expression Profiling; Humans; Mutation; RNA, Messenger/analysis; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Trans-Activators/biosynthesis; Uncoupling Agents/pharmacology; Up-Regulation; beta-Lactamases/metabolism |
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