PMID:19759044
| Citation |
Bailey, AM, Constantinidou, C, Ivens, A, Garvey, MI, Webber, MA, Coldham, N, Hobman, JL, Wain, J, Woodward, MJ and Piddock, LJ (2009) Exposure of Escherichia coli and Salmonella enterica serovar Typhimurium to triclosan induces a species-specific response, including drug detoxification. J. Antimicrob. Chemother. 64:973-85 |
|---|---|
| Abstract |
The use of triclosan within various environments has been linked to the development of multiple drug resistance (MDR) through the increased expression of efflux pumps such as AcrAB-TolC. In this work, we investigate the effect of triclosan exposure in order to ascertain the response of two species to the presence of this widely used biocide. |
| Links |
PubMed Online version:10.1093/jac/dkp320 |
| Keywords |
Biofilms/drug effects; Biofilms/growth & development; Biological Transport; Disinfectants/pharmacology; Escherichia coli K12/drug effects; Escherichia coli K12/physiology; Gene Expression/drug effects; Gene Expression Profiling; Locomotion/drug effects; Membrane Transport Proteins/biosynthesis; Oligonucleotide Array Sequence Analysis; Salmonella typhimurium/drug effects; Salmonella typhimurium/physiology; Triclosan/pharmacology |
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