PMID:19749043
| Citation |
Steenbergen, SM, Jirik, JL and Vimr, ER (2009) YjhS (NanS) is required for Escherichia coli to grow on 9-O-acetylated N-acetylneuraminic acid. J. Bacteriol. 191:7134-9 |
|---|---|
| Abstract |
The nanATEK-yhcH, yjhATS, and yjhBC operons in Escherichia coli are coregulated by environmental N-acetylneuraminic acid, the most prevalent sialic acid in nature. Here we show that YjhS (NanS) is a probable 9-O-acetyl N-acetylneuraminic acid esterase required for E. coli to grow on this alternative sialic acid, which is commonly found in mammalian host mucosal sites. |
| Links |
PubMed PMC2772488 Online version:10.1128/JB.01000-09 |
| Keywords |
Escherichia coli/genetics; Escherichia coli/growth & development; Escherichia coli/metabolism; Escherichia coli Proteins/genetics; Escherichia coli Proteins/physiology; Gene Expression Regulation, Bacterial/genetics; Gene Expression Regulation, Bacterial/physiology; N-Acetylneuraminic Acid/metabolism; Sialic Acids/metabolism |
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