PMID:19426454
| Citation |
Wang, RS, Jin, G, Zhang, XS and Chen, L (2009) Modeling post-transcriptional regulation activity of small non-coding RNAs in Escherichia coli. BMC Bioinformatics 10 Suppl 4:S6 |
|---|---|
| Abstract |
Transcriptional regulation is a fundamental process in biological systems, where transcription factors (TFs) have been revealed to play crucial roles. In recent years, in addition to TFs, an increasing number of non-coding RNAs (ncRNAs) have been shown to mediate post-transcriptional processes and regulate many critical pathways in both prokaryotes and eukaryotes. On the other hand, with more and more high-throughput biological data becoming available, it is possible and imperative to quantitatively study gene regulation in a systematic and detailed manner. |
| Links |
PubMed PMC2681065 Online version:10.1186/1471-2105-10-S4-S6 |
| Keywords |
Algorithms; Computational Biology/methods; Escherichia coli/genetics; Escherichia coli/metabolism; Gene Expression Profiling/methods; Gene Expression Regulation, Bacterial; Models, Genetic; RNA Processing, Post-Transcriptional; RNA, Untranslated/metabolism |
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