PMID:19376874
| Citation |
Ferenci, T, Zhou, Z, Betteridge, T, Ren, Y, Liu, Y, Feng, L, Reeves, PR and Wang, L (2009) Genomic sequencing reveals regulatory mutations and recombinational events in the widely used MC4100 lineage of Escherichia coli K-12. J. Bacteriol. 191:4025-9 |
|---|---|
| Abstract |
The genome of an Escherichia coli MC4100 strain with a lambda placMu50 fusion revealed numerous regulatory differences from MG1655, including one that arose during laboratory storage. The 194 mutational differences between MC4100(MuLac) and other K-12 sequences were mostly allocated to specific lineages, indicating the considerable mutational divergence between K-12 strains. |
| Links |
PubMed PMC2698400 Online version:10.1128/JB.00118-09 |
| Keywords |
Base Sequence; Escherichia coli/chemistry; Escherichia coli/genetics; Escherichia coli/metabolism; Gene Expression Regulation, Bacterial; Genome, Bacterial; Molecular Sequence Data; Mutation; Recombination, Genetic; Sequence Alignment; Sequence Analysis, DNA |
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