PMID:19015139

From EcoliWiki
Jump to navigation Jump to search
Citation

Horler, RS, Butcher, A, Papangelopoulos, N, Ashton, PD and Thomas, GH (2009) EchoLOCATION: an in silico analysis of the subcellular locations of Escherichia coli proteins and comparison with experimentally derived locations. Bioinformatics 25:163-6

Abstract

SUMMARY: EchoLOCATION is a database that provides a comprehensive analysis of the subcellular locations of Escherichia coli K-12 proteins. Locations are predicted by integrating data from a range of publicly available algorithms combined with extensive curation of experimental literature. The data can be searched in a variety of ways and can generate lists of subcellular proteomes for analysis. Experimental evidence supports the locations of over 500 envelope proteins (periplasm, inner and outer membrane). From analysis of disagreements between in silico predictions and experimental data, we provide an analysis of protein types where subcellular prediction algorithms are currently not accurate.

Links

PubMed Online version:10.1093/bioinformatics/btn596

Keywords

Algorithms; Bacterial Outer Membrane Proteins/analysis; Bacterial Outer Membrane Proteins/chemistry; Databases, Protein; Escherichia coli/metabolism; Escherichia coli Proteins/analysis; Escherichia coli Proteins/chemistry; Models, Biological; Periplasm/chemistry; Proteome/analysis; Proteomics/methods

Significance

You can help EcoliWiki by summarizing why this paper is useful

Useful Materials and Methods

You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.

Annotations

<annotationlinks/>

EcoliWiki Links

Add links to pages that link here (e.g. gene, product, method pages)

See also

References

See Help:References for how to manage references in EcoliWiki.