PMID:18997424

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Citation

Yamamoto, K, Matsumoto, F, Oshima, T, Fujita, N, Ogasawara, N and Ishihama, A (2008) Anaerobic regulation of citrate fermentation by CitAB in Escherichia coli. Biosci. Biotechnol. Biochem. 72:3011-4

Abstract

In Escherichia coli, CitB, a cognate response regulator of CitA, specifically bound to the promoter regions for mdh, citA, citC, and exuT. Transcription of these genes was induced by citrate under anaerobic conditions in a CitAB-dependent manner. Taking this together, we conclude that CitAB is the master regulatory system that activates the set of genes involved in citrate fermentation in E. coli.

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Keywords

Base Sequence; Binding Sites; Citrates/pharmacology; Escherichia coli/genetics; Escherichia coli/metabolism; Escherichia coli Proteins/metabolism; Fermentation/drug effects; Genomics; Oxygen/metabolism; Promoter Regions, Genetic/genetics

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