PMID:18776195

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Citation

Rodrigo, G, Carrera, J, Prather, KJ and Jaramillo, A (2008) DESHARKY: automatic design of metabolic pathways for optimal cell growth. Bioinformatics 24:2554-6

Abstract

The biological solution for synthesis or remediation of organic compounds using living organisms, particularly bacteria and yeast, has been promoted because of the cost reduction with respect to the non-living chemical approach. In that way, computational frameworks can profit from the previous knowledge stored in large databases of compounds, enzymes and reactions. In addition, the cell behavior can be studied by modeling the cellular context.

Links

PubMed Online version:10.1093/bioinformatics/btn471

Keywords

Algorithms; Computational Biology/methods; Databases, Protein; Escherichia coli/growth & development; Escherichia coli/metabolism; Metabolic Networks and Pathways; Phylogeny; Sequence Analysis, Protein; Software

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DESHARKY
Category:Bioinformatics_Tools

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