PMID:18236013

Citation	Horie, N, So, K, Moriya, T, Kitagawa, N, Tsutsumi, K, Nagata, I and Shinohara, K (2008) Effects of oxygen concentration on the proliferation and differentiation of mouse neural stem cells in vitro. Cell. Mol. Neurobiol. 28:833-45
Abstract	Cerebral ischemia is known to elicit the activation of neural stem cells (NSCs); however its mechanism is not fully determined. Although oxygen concentration is known to mediate many ischemic actions, there has been little attention given to the role of pathological oxygen changes under cerebral ischemia on the activation of NSCs. We investigated the effects of various oxygen concentrations on mouse neural stem cells in vitro.
Links	PubMed Online version:10.1007/s10571-007-9237-y
Keywords	Animals; Astrocytes/physiology; Basal Ganglia/cytology; Cell Death; Cell Differentiation; Cell Hypoxia; Cell Proliferation; Embryo, Mammalian/cytology; Mice; Mice, Inbred ICR; Neurons/physiology; Oxygen/pharmacology; Oxygen/physiology; Stem Cells/physiology
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