PMID:18235030

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Citation

Hutnik, CM, Pocrnich, CE, Liu, H, Laird, DW and Shao, Q (2008) The protective effect of functional connexin43 channels on a human epithelial cell line exposed to oxidative stress. Invest. Ophthalmol. Vis. Sci. 49:800-6

Abstract

To determine the role of connexin43 (Cx43) and gap junctional intercellular communication (GJIC) in the response of the human retinal pigment epithelial cell line ARPE-19 to oxidative stress.

Links

PubMed Online version:10.1167/iovs.07-0717

Keywords

Blotting, Western; Cell Communication/physiology; Cell Line; Cell Survival; Connexin 43/physiology; Connexins/metabolism; Cytoprotection; Fluorescent Antibody Technique, Indirect; Gap Junctions/physiology; Gene Silencing; Humans; Microscopy, Confocal; Oxidative Stress; Pigment Epithelium of Eye/cytology; Pigment Epithelium of Eye/drug effects; RNA Interference; Tetrazolium Salts; Thiazoles; tert-Butylhydroperoxide/toxicity

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