PMID:18234646
| Citation |
Han, P, Zhang, YY, Lu, Y, He, B, Zhang, W and Xia, F (2008) Effects of different free fatty acids on insulin resistance in rats. HBPD INT 7:91-6 |
|---|---|
| Abstract |
Much evidence demonstrates that elevated free fatty acids (FFAs) are associated with insulin resistance. However, it is not clear whether different FFAs can cause different degrees of peripheral insulin resistance. This study aimed to investigate the effects of short-term elevation of FFAs on hepatic and peripheral insulin action, and determine whether FFAs with different degrees of saturation have differential effects on hepatic insulin resistance. |
| Links | |
| Keywords |
Animals; Anticoagulants/pharmacology; Blood Glucose/metabolism; C-Peptide/blood; Dietary Fats/pharmacology; Fat Emulsions, Intravenous/pharmacology; Fatty Acids, Nonesterified/blood; Fatty Acids, Nonesterified/pharmacology; Fatty Acids, Unsaturated/pharmacology; Female; Glucose Clamp Technique; Heparin/pharmacology; Hyperinsulinism/drug therapy; Hyperinsulinism/metabolism; Insulin/blood; Insulin Resistance; Liver/drug effects; Liver/metabolism; Oleic Acid/pharmacology; Rats; Rats, Wistar |
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