PMID:18234113

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Citation

Sharpton, TJ, Neafsey, DE, Galagan, JE and Taylor, JW (2008) Mechanisms of intron gain and loss in Cryptococcus. Genome Biol. 9:R24

Abstract

Genome comparisons across deep phylogenetic divergences have revealed that spliceosomal intron gain and loss are common evolutionary events. However, because of the deep divergences involved in these comparisons, little is understood about how these changes occur, particularly in the case of intron gain. To ascertain mechanisms of intron gain and loss, we compared five relatively closely related genomes from the yeast Cryptococcus.

Links

PubMed PMC2395259 Online version:10.1186/gb-2008-9-1-r24

Keywords

Base Sequence; Cryptococcus/genetics; DNA Repeat Expansion; Evolution, Molecular; Introns; Molecular Sequence Data; Phylogeny; Recombination, Genetic; Sequence Alignment

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