PMID:18231812

Citation	Hufnagel, M, Burger, A, Bartelt, S, Henneke, P and Berner, R (2008) Secular trends in pediatric bloodstream infections over a 20-year period at a tertiary care hospital in Germany. Eur. J. Pediatr. 167:1149-59
Abstract	Over the last 20 years, a number of medical innovations with impact on the incidence of bacterial and fungal bloodstream infections (BSIs) in children have been developed and implemented. Although appropriate empirical antimicrobial therapy is a prerequisite to the successful treatment of BSIs, to date, epidemiological data on long-term microbiological trends in BSIs of hospitalized children have not been available.
Links	PubMed Online version:10.1007/s00431-007-0651-4
Keywords	Bacterial Infections/epidemiology; Bacterial Infections/microbiology; Blood/microbiology; Child; Drug Resistance, Bacterial; Germany/epidemiology; Haemophilus influenzae/isolation & purification; Humans; Inpatients; Mycoses/epidemiology; Mycoses/microbiology; Neisseria meningitidis/isolation & purification; Retrospective Studies; Sepsis/epidemiology; Sepsis/microbiology; Staphylococcus aureus/isolation & purification; Streptococcus agalactiae/isolation & purification
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