PMID:18230686

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Citation

Murphy, BS, Sundareshan, V, Cory, TJ, Hayes, D Jr, Anstead, MI and Feola, DJ (2008) Azithromycin alters macrophage phenotype. J. Antimicrob. Chemother. 61:554-60

Abstract

To investigate the in vitro effects of azithromycin on macrophage phenotype. Utilizing a mouse macrophage cell line (J774), we examined the effect of azithromycin on the properties that define classical macrophage activation (M1) and alternative macrophage activation (M2).

Links

PubMed Online version:10.1093/jac/dkn007

Keywords

Animals; Azithromycin/pharmacology; Cell Line; Cell Line, Transformed; Cytokines/biosynthesis; Cytokines/genetics; Immunophenotyping; Macrophages/classification; Macrophages/drug effects; Macrophages/immunology; Macrophages/metabolism; Mice; Mice, Inbred BALB C

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