PMID:18228005

Citation	D'Souza, DC, Braley, G, Blaise, R, Vendetti, M, Oliver, S, Pittman, B, Ranganathan, M, Bhakta, S, Zimolo, Z, Cooper, T and Perry, E (2008) Effects of haloperidol on the behavioral, subjective, cognitive, motor, and neuroendocrine effects of Delta-9-tetrahydrocannabinol in humans. Psychopharmacology (Berl.) 198:587-603
Abstract	Cannabinoids produce a spectrum of effects in humans including euphoria, cognitive impairments, psychotomimetic effects, and perceptual alterations. The extent to which dopaminergic systems contribute to the effects of Delta-9-tetrahydrocannabinol (Delta-9-THC) remains unclear. This study evaluated whether pretreatment with a dopamine receptor antagonist altered the effects of Delta-9-THC in humans.
Links	PubMed PMC2878815 Online version:10.1007/s00213-007-1042-2
Keywords	Adolescent; Adult; Antipsychotic Agents/pharmacology; Behavior/drug effects; Cognition/drug effects; Euphoria/drug effects; Female; Hallucinogens/pharmacology; Haloperidol/pharmacology; Humans; Male; Marijuana Smoking/psychology; Marijuana Smoking/urine; Memory, Short-Term/drug effects; Middle Aged; Motor Activity/drug effects; Neuropsychological Tests; Neurosecretory Systems/drug effects; Psychomotor Performance/drug effects; Substance Abuse Detection; Tetrahydrocannabinol/pharmacology; Visual Perception/drug effects
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